PRF has been granted a patent on methods of preparing and isolating collagen compositions with enhanced microstructural properties

Published: January 27, 2012

Purdue Research Foundation has been granted a patent on methods for creating and isolating collagen compositions with higher polymerization rates and improved microstructural properties.

Collagen is the most abundant protein in the human body, where it serves as a structural support for surrounding cells. As part of the extracellular matrix (ECM), collagen helps to form the connective tissue that separates cells and regulates intercellular communication. This structural function is important for new growth and wound repair, and makes collagen-based structures ideal for tissue repair or growth structures.

Purdue researchers have developed a new method for preparing collagen compositions through isolating the collagen fibers that exhibit the desired properties. Engineered ECMs that are produced with the collagen compositions created by this method have increased mechanical integrity over commercially available collagen concentrations. There are numerous clinical applications for collagen, such as tissue grafts and growing new organs.